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Cervical Cancer

Overview and Types

What is Cervical Cancer?

Cervical cancer refers to the formation of a tumor in the cervix. Rarely, it is also called pelvic cancer, as the organ is situated in the pelvic region.

The cervix is an important part of the female reproductive system that connects the vagina with the uterus. When the cells present in the cervical lining start dividing uncontrollably, it leads to the formation of a tumor.

It is possible to reduce the risk of cervical cancer through specific cervical cancer prevention and screening practices.

How Common is Cervical Cancer?

In developing countries like India, cervical carcinoma is still a burden. It is the second most common cancer diagnosed among Indian women. The risk of cervical cancer is found to increase around the age of 45 and peak at 55.

A large percentage of invasive cervical tumor cases are associated with chronic HPV infection.

What are the Different Types of Cervical Cancer?

There are different types of cervical cancer based on the cell type from which it arises. A few cervical carcinoma types are more common than the others.

1. Most Common Types of Cervical Cancer

The following are the most common types of cervical cancer:

  • Squamous Cell Carcinoma

    Squamous cell carcinoma arises from the flat cells in the ectocervix, the bottom portion of the cervix. Squamous cell carcinoma accounts for about 80–90% of cervical tumor cases and is therefore the most common type of cervical cancer.

  • Adenocarcinoma

    Adenocarcinoma arises from the glandular cells in the endocervix, the upper portion of the cervix. Adenocarcinoma of the cervix accounts for about 10–20% of cervical carcinomas.

2. Rare Types of Cervical Cancer

The following are rare types of cervical carcinoma:

  • Adenosquamous carcinomas

    Adenosquamous carcinomas, also known as mixed carcinomas, carry the characteristic features of both squamous cell carcinomas and adenocarcinomas.

  • Glassy cell carcinomas

    Glassy cell carcinomas are a rare and aggressive form of cervical carcinoma. The glassy cell carcinoma cells have a glass-like appearance when observed under a microscope, thus the name. This is one of the more aggressive types of cervical cancer, with a poor prognosis.

  • Neuroendocrine carcinomas

    Neuroendocrine carcinomas account for a small percentage of cervical carcinomas. Neuroendocrine carcinomas arise from the hormone-producing cells associated with the neuroendocrine system. It is one of the rare types of cervical carcinoma.

What are the Cervical Cancer Stages?

The staging of cervical carcinoma is done to determine the extent of the disease's spread. Cervical cancer stages 0, 1, and 2 refer to the early stages of cervical tumors, while cervical cancer stages 3 and 4 refer to advanced-stage cervical cancers. The following are the indicators of different stages of cervical cancer:

1. Stage 0 Cervical Cancer

Stage 0 cervical cancer refers to the earliest stage, where only cervical cell abnormalities are observed. The cancer cells are present on the surface and have not invaded the deeper tissues.

2. Stage 1 Cervical Cancer

In this stage, cervical carcinoma remains confined to the organ and has not spread to the surrounding tissues or organs. Stage 1 cervical tumors have a favorable prognosis.

3. Stage 2 Cervical Cancer

Stage 2 cervical cancer means that the disease has begun to spread beyond the cervix but is still confined to the pelvic region. To treat stage 2 cervical carcinoma, doctors often recommend a multimodal treatment approach.

4. Stage 3 Cervical Cancer

In stage 3, the disease has spread to the lower part of the vagina or the pelvis's side walls. Stage 3 cervical carcinoma needs an aggressive treatment regimen.

5. Stage 4 Cervical Cancer

In stage 4, the disease has advanced significantly; from the pelvic region to distant sites, such as the bladder, rectum, or other organs, the disease has spread to various parts of the body. It will need a multimodal approach, and often the treatment goal is to delay disease progression, prolong survival, reduce the pain and discomfort caused by the disease, and improve the quality of life.

Symptoms and Causes

Cervical cancer may not have any symptoms in its early stages, and even if they do appear, they are mild and can only be detected by a doctor. In most cases, symptoms of cancer of the cervix become apparent only in the advanced stages, when the disease has spread to other parts of the body.

A few symptoms of cervical cancer may be similar to symptoms of other cervix problems, and therefore, they may be ignored in some cases. This may lead to a delayed diagnosis and a poor treatment prognosis.

Paying attention to the different signs and symptoms of cervical cancer and understanding the possible causes of cervical cancer can aid in the early detection and timely treatment of this condition.

Who is Mainly Affected by Cervical Cancer?

Cervical cancer is one of the most common cancers among women. The risk of cervical cancer is found to increase around the age of 45 and peak around the age of 55.

Those who have had an HPV infection for years have a higher chance of developing cervical cancer.

That said, anyone can get diagnosed with cervical cancer, and it is therefore important to undergo regular screening, which helps in the early detection and timely treatment of cervical cancer.

Most Common Signs and Symptoms of Cervical Cancer

Not all women with cervical cancer experience the same symptoms. Being aware of the different symptoms of cervical cancer can help women seek medical attention at the right time and put themselves a step ahead of the disease. The following are some of the important cervix cancer signs and symptoms:

1. Abnormal Vaginal Bleeding

Women must keep an eye on abnormal vaginal bleeding, as this is one of the most common symptoms of cervical cancer. Bleeding between periods, bleeding after sexual intercourse, or bleeding after menopause are some of the signs of cervical cancer, and it is important to see a doctor for a definitive diagnosis.

2. Unusual Vaginal Discharge

Any changes in the vaginal discharge with respect to its volume, texture, odor, and color should not be ignored, as this is also one of the important stage 1 cervical cancer symptoms.

3. Pelvic Pain

Women with cervical cancer may experience pain, which may range from a dull ache to pronounced discomfort. If this pain is persistent, one must see a doctor for a proper evaluation.

4. Pain During Sexual Intercourse

Women with cervical cancer may also experience pain during sexual intercourse, also known as dyspareunia. This may or may not be accompanied by abnormal bleeding. This symptom should not be ignored, as it is one of the most important signs of cervical cancer.

5. Painful Urination

Pain and discomfort while urinating could also be cervix cancer early symptoms. That said, painful urination can be caused by other problems too, and therefore, it is advised to see a doctor for a proper evaluation. This could be one of the stage 2 cervical cancer symptoms.

6. Changes in Menstrual Cycle

Women with cervical cancer may experience menstrual irregularities, namely heavier periods, prolonged periods, and bleeding between periods. In such cases, women must seek immediate medical attention.

7. Weight Loss and Fatigue

As the disease progresses, women with cervical cancer may experience unintended weight loss and extreme tiredness. This could be one of the cervical cancer stage 3 symptoms.

Cervical Cancer Types & Their Symptoms

The symptoms of cervical cancer may vary depending on the type of cancer. The following are the possible symptoms of different types of cervical cancer:

1. Symptoms of Squamous Cell Carcinoma

Squamous cell carcinoma may present with symptoms like vaginal bleeding, pain during intercourse, changes in the vaginal discharge, and discomfort in the pelvic region.

2. Symptoms of Adenocarcinoma

This type of cervical cancer may present with unusual vaginal discharge and pain and discomfort in the pelvic region.

3. Symptoms of Adenosquamous Carcinomas

Adenosquamous carcinomas can present with symptoms of both squamous cell carcinomas and adenocarcinomas. Women with adenosquamous carcinomas may experience vaginal bleeding, vaginal discharge, pain, and discomfort in the pelvic region.

4. Symptoms of Glassy Cell Carcinomas

This rare type of cervical cancer may cause symptoms like bleeding, discomfort, and pain.

5. Symptoms of Neuroendocrine Carcinomas

Women with neuroendocrine carcinoma of the cervix experience abnormal vaginal discharge and bleeding, pelvic pain, and pain during intercourse.

What are the Causes of Cervical Cancer?

Presently, the exact cause of cervical cancer is unknown. However, over the years, a few factors that can increase the risk of cervical cancer have been identified.

1. HPV Infection

Human papillomavirus (HPV) infection is one of the biggest risk factors for cervical cancer, and it could be one of the potential causes of cervical cancer.

2. Early Sexual Activity

Becoming sexually active at a young age is also found to increase cervical cancer risk in women.

3. Smoking

Smoking is one of the potential causes of cervical cancer, as tobacco contains harmful chemicals that can weaken the immune system and make one more susceptible to HPV infection.

4. Long-Term Use of Birth Control Pills

Although the connection between long-term use of oral contraceptives and cervical cancer risk is not fully understood, it is also observed to be one of the possible risk factors or possible causes of cervical cancer.

5. Multiple Pregnancies

Multiple full-term pregnancies are also considered one of the possible causes of cervical cancer.

6. Multiple Sexual Partners

Having multiple sexual partners is also found to increase one’s chances of developing cervical cancer due to increased exposure to the HPV virus.

7. Diethylstilbestrol (DES) Exposure

Women who are exposed to diethylstilbestrol in utero (prenatal exposure) have a higher chance of being diagnosed with cervical cancer.

8. Genetic Factors

Having a positive family history of cervical cancer or having certain inherited genetic disorders that are associated with cervical cancer development can increase one’s chances of developing cervical cancer.

9. Socioeconomic Factors

A lack of awareness, low levels of education and income, and limited access to healthcare may possibly increase one’s risk of developing cervical cancer.

10. Weak Immune System

A weaker immune system, which may be caused by certain diseases like HIV/AIDS, can also be a reason for cervical cancer.

11. Poor Hygiene and Sanitation

Poor hygiene practices may also become a risk factor for cervical cancer.

When to See an Oncologist?

Certain signs and symptoms of cancer of the cervix are similar to those of other less serious gynecological problems. However, it is important not to ignore the different signs of cervical cancer, especially if they last for more than two weeks or begin to worsen. Promptly seeing a doctor in such cases can support an early diagnosis and timely treatment of cervical cancer.

Diagnosis and Treatment

Cervical cancer is a significant health concern in India, and it necessitates a deep understanding of the disease and a thorough exploration of its diagnostic and treatment protocols. At HCG, our specialists employ modern diagnostic and treatment protocols to diagnose, treat, and manage cervical cancer.

Procedures or Tests for Diagnosis of Cervical Cancer

Specialists use multiple tests for cervical cancer diagnosis, and upon arriving at a conclusive diagnosis, they create a personalized treatment plan. The following are the most recommended tests for the diagnosis of cervical cancer:

1. Pap Smear (Pap Test)

A Pap smear test, also considered a cervical cancer screening tool, involves collecting and examining cells from the cervical lining for abnormalities.

2. HPV DNA Test

The HPV DNA test involves collecting cervical cells and examining them for the presence of the DNA of high-risk human papillomavirus (HPV) strains that are associated with cervical cancer.

3. Colposcopy

Colposcopy involves visually examining the cervix for the presence of precancerous lesions or tumors. A colposcope is a specialized instrument that is externally positioned near the vaginal opening, and the regions of the vulva, vagina, and cervix are examined for any abnormalities.

4. Biopsy

A biopsy is an important diagnostic test for cervical cancer and is usually recommended for a conclusive diagnosis. During this procedure, a small sample of the cervix tissue is removed and examined under a microscope to look for the presence of cancerous cells.

  • Endocervical Curettage (ECC)

    Endocervical curettage is a type of biopsy wherein a spoon-like instrument, called a curette, is used to scrape tissue from the endocervical canal. The tissue collected is examined for the presence of cancerous cells.

  • Loop Electrosurgical Excision Procedure (LEEP)

    The loop electrosurgical excision procedure (LEEP) is a type of biopsy wherein a thin wire loop is used to collect the cervical tissue sample. Electric current is passed through the wire loop, which then excises the tissue from the suspected area, and it is further examined in the lab for the presence of cancerous cells.

  • Conization (Cone Biopsy)

    A cone biopsy is a form of biopsy wherein a cone-shaped piece of cervix tissue is collected. This procedure allows technicians to obtain a larger tissue sample. A cone biopsy may be recommended to treat abnormal cellular changes and precancerous lesions.

5. Imaging Tests

Imaging tests help in obtaining images of the internal structures of the organ examined, in this case, the cervix. Apart from the diagnosis of cervical cancer, imaging tests can also help in disease staging, treatment response monitoring, and relapse evaluation. The following are the imaging tests used for the diagnosis of cervical cancer:

  • CT Scans

    Computed tomography (CT) scans are recommended to study the anatomical structure of the cervix. This imaging technique uses X-rays to obtain detailed images of the organ.

  • MRI scans

    Magnetic resonance imaging (MRI) scans use powerful magnetic fields and radio waves to create detailed images of the organ. Along with being an important diagnostic test for cervical cancer, it also serves as a staging tool for cervical cancer.

  • PET Scans

    Positron emission tomography (PET) is another important imaging technique used in diagnosing cervical cancer through radiotracers. Unlike other imaging tests, a PET scan is used to study the biochemical activities of the tumor. PET scans help in assessing nodal involvement and distant metastases. For more accurate results, PET is often combined with CT.

What are Effective Cervical Cancer Treatments?

Upon arriving at a definitive diagnosis, a personalized cervical cancer treatment plan is devised. The treatment may be unimodal (one treatment) or multimodal (a combination of two or more treatments) depending on multiple factors, such as the type of cervical cancer, its stage, its grade, the patient’s age, the patient’s overall health, and lastly, the patient’s preferences.

1. Surgery

Surgery is often the first line of cervical cancer treatment or pelvic cancer treatment. Surgery is often recommended as a treatment for stage 1 cervical cancer. The goal of surgery is to remove as much tumor tissue as possible. Surgery may remove only the tumor or the entire organ, depending on the extent of the disease’s spread. Surgery is often combined with other treatment options like chemotherapy and radiation therapy to improve the overall effectiveness of the treatment.

  • Hysterectomy

    Hysterectomy refers to the removal of the uterus. It is recommended as a cervical cancer treatment to treat cancer that has spread beyond the cervix but is confined to the pelvic area.

  • Trachelectomy

    Trachelectomy is recommended as an early-stage cervical cancer treatment, wherein the cervix is removed and the uterus is left intact. This form of cervical cancer therapy is highly recommended for patients who wish to preserve their fertility.

  • Lymph Node Dissection

    This procedure involves the removal of lymph nodes close to the cervix and in the pelvic region and their examination for the presence of cancerous cells. Lymph node dissection plays a pivotal role in disease staging and guides cervical cancer treatment decisions.

2. Radiation Therapy

Radiation therapy, or radiotherapy, is also one of the important cervical cancer treatment options. Radiotherapy for cervical cancer involves targeting the tumor with powerful and intense radiation beams, which damage the DNA structure of the tumor cells and stop them from growing. With the advanced technology available today, we can precisely target the tumor while reducing damage to the nearby healthy tissues.

Radiotherapy for cervical cancer is often recommended after surgery to destroy the residual cancer cells, which is important in reducing the risk of recurrence.

  • External Beam Radiation

    External beam radiation therapy is a form of radiation therapy wherein the radiation beams are delivered from an external source through a linear accelerator. External beam radiation therapy is highly precise and effective in shrinking tumors, destroying residual cancer cells, alleviating pain and discomfort associated with cervical cancer, and reducing the risk of recurrences.

  • Brachytherapy

    Brachytherapy for cervical cancer, or internal beam radiation therapy, involves placing a radiation source inside (interstitial) or close to the tumor (intracavitary). This form of cervical cancer therapy facilitates better targeting and high-dose radiation delivery while minimizing damage to nearby tissues.

3. Chemotherapy

Chemotherapy is another important cervical cancer treatment option, wherein specialists recommend potent medication for cervical cancer management. Cervical cancer chemotherapy involves the use of powerful drugs to destroy cancerous cells throughout the body. This treatment is usually recommended if the disease has spread to different organs in the body.

Chemotherapy may be administered before the surgery (neoadjuvant chemotherapy) or after the surgery (adjuvant chemotherapy) to shrink the tumor or destroy the residual cancer cells, respectively. Cervical cancer chemotherapy is administered orally or intravenously, depending on individual case parameters.

  • Systemic Chemotherapy

    Systemic chemotherapy involves administering powerful anti-cancer drugs into the bloodstream; these drugs circulate throughout the body and destroy the cancer cells. Systemic chemotherapy is recommended for advanced-stage cervical cancers. Systemic chemotherapy for cervical cancer may or may not be combined with other cervical cancer treatment options. Systemic chemotherapy is used to slow down the disease progression and alleviate symptoms associated with cervical cancer.

  • Concurrent Chemoradiation

    Concurrent chemoradiation is also an important cervical cancer treatment approach that combines chemotherapy with radiation therapy. The enhanced effectiveness of this combined treatment approach positively impacts clinical outcomes and supports better success rates. Chemotherapy may sensitize the cancer cells to radiation therapy, which improves the overall treatment effectiveness. Concurrent chemoradiation helps shrink the tumor size, destroy the residual cancer cells, and delay disease progression.

4. Targeted Therapy

Targeted therapy is one of the latest cervical cancer treatments, wherein specific molecules and cellular pathways that are responsible for cancer growth are targeted. Cervical cancer medicines administered as a part of targeted therapy block the activity of those specific molecules and pathways and affect cancer growth. Targeted therapy is often recommended when standard treatments fail to show a desirable response. One of the biggest advantages of targeted therapy is that it significantly reduces damage to healthy tissues in the body.

5. Immunotherapy

Immunotherapy is one of the new treatments for cervical cancer, wherein the patient’s immune system is re-engineered to identify and attack the cancer cells in the body. For cervical cancer, immune checkpoint inhibitors are administered as a part of immunotherapy, and they work by blocking the proteins that stop the immune system from identifying and attacking the cancer cells. Immunotherapy for cervical cancer may be recommended when the standard treatments become ineffective, or it may be recommended along with the standard treatments for better treatment effectiveness.

6. Clinical Trials

Clinical trials involve testing new drugs, treatment combinations, and treatment approaches for effective cervical cancer management. Those cervical cancer patients who have exhausted all their treatment options may enroll in clinical trials, as these provide them with an option to try out new treatments before they are widely available.

Participation in clinical trials is voluntary, and patients must have a detailed discussion with their expert team before enrolling, as not all patients are eligible to participate in a clinical trial. To learn more about enrolling in clinical trials for cervical cancer management, please talk to a specialist.

Why Choose HCG for Treatment and Diagnosis of Cervical Cancer?

As the best cervical cancer treatment hospital in India, HCG is committed to delivering the highest quality diagnostic and treatment support to cervical cancer patients across the country. The entire team at HCG practices a personalized and patient-centric care approach wherein the patient is at the center of their treatment journey and receives the treatment, care, and attention that are designed just for them.

Along with access to leading-edge diagnostic and treatment facilities, patients are also given access to clinical trials to help them access newer treatment approaches to manage and improve their condition. The comfortable care setting at HCG has helped millions of patients receive the best treatment for cervical cancer.

Prevention and Risk Factors

Cervical cancer is one of the most common cancers among Indian women. Although we do not know the exact cause of cervical cancer, it is understood that a few lifestyle and non-lifestyle-related factors can contribute to increased cervical cancer risk.

Becoming aware of various cervical cancer risk factors and following appropriate cervical cancer preventive measures can help women reduce their cervical cancer risk.

Most Common Cervical Cancer Risk Factors

One’s risk of developing cervical cancer is influenced by multiple factors. These may be specific lifestyle and non-lifestyle factors. Lifestyle factors are also called controllable or modifiable factors, and non-lifestyle factors are referred to as uncontrollable or non-modifiable factors.

Having a better understanding of these risk factors plays a pivotal role in potential cervical cancer prevention and early detection.

1. Age

Increasing age is an important risk factor for cervical cancer. The risk of cervical cancer increases around the age of 45 and peaks at age 55.

2. Family History

Having a positive family history of cervical cancer or certain other cancers can increase one’s chances of developing cervical cancer. It is also understood that certain genetic factors can influence an individual’s susceptibility to HPV infection, which is also an important risk factor for cervical cancer.

3. Diethylstilbestrol (DES)

Diethylstilbestrol, or DES, is an artificially synthesized non-steroid estrogen that was recommended to prevent miscarriages between the 1940s and 1970s. Its usage was stopped when many doctors found a strong association between uterine exposure to DES and the incidence of cervical cancer and vaginal cancer. Women whose mothers were prescribed the drug diethylstilbestrol (DES) during pregnancy may have a higher chance of developing cervical cancer. DES-exposed women should opt for regular cervical cancer screening.

4. Early Onset of Menstruation

The early onset of menstruation is also an important risk factor for cervical cancer. Early menstruation causes women to have increased exposure to hormones that impact cervical cell growth. Those who have had their first period before the age of 12 should pay extra attention to their health, follow appropriate cervical cancer preventive measures, and opt for cervical cancer screening.

5. Early Childbearing

Getting pregnant or having multiple pregnancies before the age of 20 can increase one’s risk of developing cervical cancer. The hormonal changes due to early pregnancy and the increased susceptibility to HPV infection contribute to the increased cervical cancer risk.

6. Having Many Full-Term Pregnancies

Another important risk factor for cervical cancer is having multiple full-term pregnancies. Women who have multiple pregnancies experience hormonal changes and have repeated exposure to HPV, and these factors contribute to their increased cervical cancer risk.

7. Race and Ethnicity

Ethnicities prevalent in developing countries are prone to having an increased cervical cancer risk. Hispanic and black women are found to have a higher risk of developing cervical cancer. Also, a few studies have found that certain Asian ethnic groups are also at increased risk of cervical cancer. A lack of awareness, lower rates of screening, and limited access to healthcare facilities may contribute to this disparity.

8. Socioeconomic Factors

Many reports suggest that certain socioeconomic factors also contribute to an increased risk of developing cervical cancer. Lower levels of education, income, and health literacy, along with limited access to healthcare facilities, are some of the common socioeconomic factors that can influence the incidence of cervical cancer.

9. History of Sexually Transmitted Infections (STIs)

Reports suggest that having certain sexually transmitted infections (STIs), such as gonorrhea and chlamydia, can increase one’s cervical cancer risk. Inflammation and cellular changes caused by these infections can make one more susceptible to HPV infection, which, in turn, increases the cervical cancer risk.

10. Weak Immune System

A compromised immune system, or weakened immune system, makes an individual more susceptible to persistent infections like HPV and subsequent cervical cancer formation. A compromised immune system may be caused by diseases like HIV/AIDS, organ transplants, immunosuppressants, or other lifestyle factors. Those with a weakened immune system should take appropriate measures to reduce the risk of infection and opt for regular screening.

11. Smoking

Smoking is also identified as one of the cervical cancer risk factors. The carcinogens present in tobacco damage cervical cells and lead to inflammation, which can increase cervical cancer risk. It may also weaken the immune system, which is, again, a risk factor for cervical cancer.

12. Obesity

Obesity is also one of the most important cervical cancer risk factors. Obesity causes inflammation and hormonal imbalances in the body, which, in turn, increase the risk of cervical cancer. Also, obese people tend to have a weaker immune system, which may make them more susceptible to HPV infection and thereby cervical cancer.

13. Long-term Use of Oral Contraceptives

Using oral contraceptives for an extended period may increase one’s risk of developing cervical cancer. For more information on the consumption of oral contraceptives and the possible cervical cancer risk, one must talk to a specialist.

How To Avoid/Prevent Cervical Cancer

Although there are no known ways to prevent cervical cancer, there are a few measures that can help women reduce their cervical cancer risk. The following are the important measures that can help women achieve possible prevention of cervical cancer:

1. HPV Vaccination

HPV infection is one of the most important cervical cancer risk factors. Vaccination against HPV is administered as a part of primary prevention for cervical cancer. HPV vaccination should be taken between the ages of 9 and 14. However, it can be taken until age 45. HPV vaccination may be administered in two or three doses, depending on the patient's age.

2. Safe Sexual Practices

Reducing the risk of HPV infection is an important measure for cervical cancer prevention. Safe sex habits are an important preventive measure and are part of primary prevention for cervical cancer. Important safe sex habits include using condoms, avoiding multiple sexual partners, and avoiding unusual sexual practices.

3. Regular Cervical Screenings

Regular cervical screening can help catch cervical cancer in its early stages and prevent advanced-stage cancers. Commonly, cervical cancer screening involves tests like Pap tests and HPV tests. Pap tests help in looking for abnormal changes in the cells that line the cervix. HPV tests are performed to look for the presence of HPV, especially types 16 and 18, in the cell sample collected from the cervical canal. Cancer screening falls under the category of secondary prevention for cervical cancer.

4. Quit Smoking

Since tobacco contains harmful chemicals, quitting smoking can help one reduce their risk of developing HPV infection and cervical cancer. Smoking cessation falls under the category of primary prevention for cervical cancer.

5. Healthy Diet

The human body needs nourishment to fight against various diseases, including cancer. It is important to have a balanced diet that comprises whole grains, lean proteins, fruits, and vegetables that are rich in essential nutrients. Consuming a balanced diet plays an important role in reducing the risk of cervical cancer.

6. Physical Activity

Engaging in regular physical activity can also play a significant role in reducing cervical cancer risk. It helps regulate hormones, boosts the immune system, and contributes to overall better health.

7. HPV Awareness

It is important to educate oneself on various aspects of cervical cancer. Learning about the risk factors, preventive measures, and screening tests available for cervical cancer can help women reduce their cervical cancer risk. HPV awareness falls under the category of primary prevention for cervical cancer.

8. Maintain Regular Health Check-ups

Regular health check-ups or screenings can aid in early detection and prevent advanced-stage cervical cancer.

Cervical Cancer Vaccination for Young Adults

It is important to note that 100% prevention and control of cervical cancer are not possible as we do not know the exact cause of the disease.

HPV vaccination is considered one of the most effective preventive measures for cervical cancer.

HPV vaccination is recommended as a cervical cancer preventive measure for girls between the ages of 9 and 26.

Presently available HPV vaccines include Cervarix, Gardasil, and Gardasil 9, along with the country’s first ingenious tetravalent vaccine, Cervavac. These vaccines provide protection against the following HPV strains:

1. Cervavix: HPV 16 and 18

2. Gardasil: HPV 6, 11, 16, and 18

3. Gardasil 9: HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58

4. Cervavac: HPV 6, 11, 16, and 18

HPV 16 and 18 are found to be responsible for about 70% of HPV-related cervical cancers, and all the vaccines listed above confer protection against these strains. Types 6 and 11 are responsible for anogenital warts.

It is interesting to note that these vaccines not only reduce the risk of cervical cancer but also other cancers like vaginal cancer, vulvar cancer, anal cancer, and oropharyngeal cancer.

For all these reasons, it is important for young adults to consider taking the HPV vaccination to protect themselves against cervical cancer and other cancers.

Although HPV vaccination reduces the risk of cervical cancer significantly, it does not prevent it. Therefore, it is important for women to undergo regular cervical cancer screening even after taking the vaccine.

Who is at High Risk of Cervical Cancer?

There are multiple factors that contribute to cervical cancer risk. Women above age 45, women who have a family history of cervical cancer, those who have been exposed to DES in utero, those who have had early menstruation, early pregnancy, or multiple pregnancies at a very young age, those who lead a sedentary life, and those who smoke are found to have a higher chance of developing cervical cancer.

Conclusion

Cervical cancer is a significant burden in India. It is also found to be more common in women from rural areas than in women from urban areas. A lack of awareness, limited access to screening facilities, fear associated with the disease, etc., have become the biggest contributors to the increasing incidence. Becoming aware of this cancer, its early signs and symptoms, and its risk factors helps reduce the risk of this condition and ensure timely medical attention.

Frequently Asked Questions

In most cases, cervical carcinoma does not stop periods. However, it may cause various other problems associated with the menstrual cycle, including irregular bleeding, bleeding between periods, bleeding after menopause, and bleeding heavier than usual.

It is important to note that these problems are caused by other, less severe health conditions, too. Therefore, for a definitive diagnosis, it is necessary to see a doctor.

No, cervical carcinoma is not visible to the naked eye, especially in the early stages. However, as the disease progresses, one may start experiencing various symptoms. These signs and symptoms include abnormal bleeding between periods, after sexual intercourse, or after menopause. Unusual vaginal discharge, pain during intercourse, or pelvic pain could also be symptoms of this condition.

One must note that relying solely on visual cues can lead to a delayed diagnosis and a poor prognosis. Instead, it is advisable to opt for regular screening, which aids in early detection and timely cervical cancer treatment.

There is no such thing as "type 2 cervical cancer." The categorization of this disease is based on types (e.g., squamous cell carcinomas, adenocarcinomas, adenosquamous carcinomas, etc.) and 4 stages of cervical cancer (0 to IV).

Cervical carcinoma may affect women of various age groups; however, the risk significantly increases around the age of 45 and peaks around the age of 55.

Since the cervix is situated within the body, it is not possible to feel the tumor externally. Abnormal bleeding, pain, or discomfort are more commonly seen symptoms in cervical carcinoma patients.

Unusual discharge due to a cervical tumor can vary in color, consistency, and odor. The discharge may be pink, brown, or bloody. It may also be foul-smelling. Abnormal vaginal discharge can be caused by various other conditions, too. Therefore, it is important to see a doctor for a conclusive diagnosis.

Cervical cancer is one of the most common cancers among Indian women. Possible reasons for this include a lack of awareness, limited access to regular screening, delayed diagnosis, etc. However, in recent years, significant efforts have been made in the direction of increasing awareness about this cancer and encouraging women to take HPV vaccinations and opt for regular screening.

Yes, it is possible to reduce the risk of a cervical tumor significantly. Chronic HPV infection is an important risk factor for cervical carcinoma, and vaccination against this virus can help reduce the risk of this cancer type. Along with HPV vaccination, regular screening can also help detect pre-cancerous changes way before they form cancer. Lastly, opting for safe sexual practices can also help reduce the risk of this condition.

Cervical cancer is commonly found to start in the squamocolumnar junction, or transformational zone, where the ectocervix (outer part of the cervix) and endocervix (inner part of the cervix) meet. Commonly, it is a persistent HPV infection, which is caused by certain HPV strains, that leads to precancerous lesions that, if left untreated, can transform into cancer. Other factors, like hereditary cervical cancer and certain genetic disorders, smoking, suppressed immunity, etc., may also lead to cervical cancer.

Many reports suggest that those with cervical cancer often have a vitamin D deficiency. However, this link is not fully understood. One of the possible reasons for this could be vitamin D’s role in immune function. The poor immunity caused by vitamin D deficiency may make one more susceptible to HPV infection, which is a direct risk factor for cervical cancer.

Certain lifestyle factors, or modifiable factors, can increase cervical cancer risk in women. Engaging in unprotected sexual intercourse, having multiple sexual practices, smoking, not opting for regular screening, poor hygiene practices, etc. are some of the important lifestyle factors that may act as possible cervical cancer reasons.

HPV infection, which is sexually transmitted, is one of the possible cervical cancer causes. It is possible for women to get HPV infections from men. If this infection becomes persistent and is not treated, it may lead to cervical cancer. Opting for HPV vaccination and practicing safe sex can help reduce cervical cancer risk in women.

Cervical cancer typically starts with the transformation zone cells on the cervix, where the squamous epithelial cells meet the glandular cells. These cells are most susceptible to HPV infection and abnormal changes that may lead to cancer.

Having multiple sexual partners is identified as one of the possible cervical cancer causes, as it increases the risk of HPV exposure. Opting for safer and healthier sexual practices, on the other hand, can help one reduce cervical cancer risk.

The following factors have been found to increase the risk of cervical cancer:

  • Persistent HPV infection
  • Early pregnancies and multiple pregnancies
  • Having multiple sexual partners
  • Compromised immune system
  • Smoking
  • Poor hygiene
  • Not opting for regular screening
  • Long-term usage of birth-control pills
  • Family history of cervical cancer

Yes. Cervical cancer is treatable. There are multiple treatment options available for cervical cancer. The success rates depend on the stage at which the disease is diagnosed. Early-stage cervical cancers are found to have better success rates than advanced-stage cervical cancers.

Some studies have reported that long-term use of oral contraceptives (birth control pills) may slightly increase the risk of cervical cancer. For more information on the use of oral contraceptives and the cervical cancer risk associated with them, it is advisable to talk to a specialist.

The treatment administered for cervical cancer depends on individual case parameters. No two patients with cervical cancer can undergo the same treatment. A treatment plan that may work for one patient may not work for another.

Surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy are the different treatment options available for cervical cancer, and they may be administered individually or in combination with one another. Before devising a customized treatment plan, factors like the type of cervical cancer, its stage, its grade, the patient’s overall health status, and their preferences are considered.

For all these reasons, it is not possible to identify one treatment as the most common treatment for cervical cancer.

It is possible to treat cervical cancer successfully, provided it is caught and treated in its early stages. Regular screening, being mindful of different cervical cancer symptoms, and lastly, seeing a specialist when something is not normal can help in the early detection of cervical cancer.

That said, no treatment is considered a cure for cervical cancer as of now.

The latest treatments available for cervical cancer include targeted therapy and immunotherapy. Both of these treatments specifically target the cancer cells and therefore reduce the damage to healthy cells. Often, these treatments are recommended when the standard treatments become ineffective. In some cases, they are recommended along with standard treatments to improve the overall effectiveness of the treatment.

A blood test may be one of the tests recommended for the diagnosis of cervical cancer. Blood tests are written to look for specific tumor markers in the blood. However, a blood test alone cannot confirm the diagnosis.

Ultrasound may not be one of the most recommended tests for cervical cancer visualization and diagnosis. However, it may be used to evaluate the size of the tumor and the extent of the disease’s spread. Other imaging tests, such as MRI scans, PET scans, and CT scans, provide a better visualization of cervical cancer.

Yes, cervical cancer can be easily detected through routine screening tests such as Pap smears, HPV tests, and colposcopy. These tests help specialists look for abnormal cellular changes in the cervix or precancerous lesions that might become cancerous. It is possible to treat these abnormalities effectively and reduce the risk of cervical cancer.

Yes, brachytherapy can be effective for cervical cancer. It is a form of radiation therapy for cervical cancer wherein the radiation source is placed inside or very close to the tumor. The radiation emitted by this radiation source damages cancer cells and reduces their growth. The biggest advantage of administering brachytherapy, or internal radiation therapy, for cervical cancer is that it allows high-dose, targeted radiation delivery while reducing damage to nearby tissues.

There are no specific vitamins that guarantee cervical cancer prevention. However, a balanced diet that is rich in lean proteins, whole grains, fruits, and vegetables can improve overall health and help reduce the risk of developing multiple cancers, including cervical cancer.

There are no specific vegetables that can prevent cervical cancer. Vegetables, in general, are an excellent source of necessary minerals, vitamins, antioxidants, and dietary fibers, and their regular consumption can improve overall health and reduce the risk of various types of cancer, including cervical cancer.

Yes, obesity can increase cervical cancer risk. According to doctors, having excess body fat, especially around the abdomen, leads to chronic inflammation and hormonal imbalances, which are important risk factors for cancer formation. Along with this, obese individuals also have a weakened immune system and a reduced immune response, which makes them more susceptible to HPV infection, which is also one of the biggest risk factors for cervical cancer.

Breast cancer and cervical cancer arise from different tissues and are two distinct types of cancer. Being diagnosed with breast cancer does not directly increase one’s cervical cancer risk. It is important to note that it is possible to be diagnosed with two unrelated cancers at the same time. Appropriate preventive measures and regular screening can support effective management of breast and cervical cancers.

“How to avoid cervical cancer?” or “How to prevent cervical cancer?” is a common question asked by many. However, it is not possible to avoid cervical cancer completely. However, one may follow certain cervical cancer precautions that can reduce the risk of cervical cancer:

  • Practicing safe sex habits
  • Avoiding multiple sexual partners
  • Receiving HPV vaccination
  • Quitting smoking
  • Eating healthy foods
  • Having an active lifestyle

The preventive strategies for cervical cancer are broadly classified into three levels:

  • Strategies for primary prevention of cervical cancer include HPV vaccination, practicing safe sex habits, and having a healthy lifestyle.
  • Strategies for secondary prevention of cervical cancer include regular cervical cancer screening through Pap tests and HPV tests.
  • Strategies for tertiary prevention of cervical cancer include timely treatment, appropriate follow-up care, and supportive care.

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