Neuroblastoma Cancer: Symptoms, Signs and Causes

Neuroblastoma is more commonly seen in children. Childhood neuroblastoma symptoms include persistent fatigue, weakness, diarrhea, abdominal pain, and bloating. The neuroblastoma symptoms in adults are almost similar to those in children. Although the disease's exact cause is unknown, it is believed to occur due to mutations, congenital anomalies, and chromosomal aberrations.

Who is most commonly affected by Neuroblastoma Cancer?

Although neuroblastoma may occur in any individual, some are at a relatively higher risk of developing this condition. Neuroblastoma most commonly affects children and individuals with a genetic predisposition to neuroblastoma, chromosomal aberrations, and MYCN amplification, people of specific races and ethnicities, and individuals who are exposed to environmental factors.

What are the Signs and Symptoms of Neuroblastoma Cancer?

Some of the neuroblastoma cancer symptoms are:

What are the Causes of Neuroblastoma Cancer?

When it comes to understanding what causes neuroblastoma, there is no concrete information on the exact cause. However, some factors do increase the risk of neuroblastoma, and they are referred to as risk factors or possible causes. The following are the possible causes of neuroblastoma:

When to see an Oncologist?

The patients should consult with the oncologists if they experience symptoms of concern, such as persistent fever, abdominal pain, sudden change in bowel habits, unexplained weight loss, constant fatigue, severe and persistent diarrhea, weakness, leg pain, back pain, and breathing problems.


The neuroblastoma signs and symptoms are pain, high fever, fatigue, loss of appetite, bloating, urinary incontinence, high blood pressure, bulging eyes, breathing problems, uncontrolled eye movements, and pale skin. The causes of neuroblastoma are age, chromosomal aberrations, mutations, MYCN amplification, and environmental factors.

Frequently Asked Questions

Commonly observed symptoms of neuroblastoma include pain in the bones, back, or legs, fatigue, high fever, loss of appetite, bulging eyes, pale skin, urinary symptoms, bowel changes, breathing problems, neurological symptoms, bleeding, mobility problems, uncontrolled eye movements, bloating, and hypertension.

Individuals with neuroblastoma, especially those with advanced neuroblastoma, may experience high fever, fatigue, weakness, and pain. The patients experience sickness and tiredness.

There are no studies to suggest vaccines as the cause of neuroblastoma.

The characteristics of a neuroblastoma lump depend on various factors, including age, size, and location. The lump may be irregularly shaped, firm, and sometimes move on touching.

Patients with a family history of neuroblastoma are at an increased risk of developing this condition, suggesting a hereditary link.

Several factors contribute to the increased trend of neuroblastoma in infants. These include genetic predisposition, embryonic origin, spontaneous mutation, and environmental factors.