Parathyroid Cancer: Symptoms, Signs, and Causes

Awareness of various parathyroid cancer symptoms, like frequent urination, excessive thirst, tiredness, etc., is crucial. Causes often include genetic mutations and radiation exposure. Understanding these factors aids in the prevention and timely medical intervention for parathyroid cancer.

What are the Parathyroid Cancer Symptoms and Signs?

Not all patients experience the same parathyroid cancer symptoms. Also, the severity of these symptoms may vary. The following are the parathyroid tumor signs and symptoms:

Other Parathyroid Cancer Symptoms

Having a Lump in Your Neck

The presence of a palpable lump in the neck is a notable symptom of parathyroid cancer. This lump is often associated with the enlargement of the affected parathyroid gland. While parathyroid tumors are generally not palpable, an enlarged gland can sometimes be felt, prompting further investigation into potential parathyroid issues.


Hoarseness is a symptom that may indicate involvement of the recurrent laryngeal nerve, which can be affected by the growth of parathyroid tumors. This nerve disruption can lead to changes in vocal cord function, resulting in hoarseness. Individuals experiencing persistent hoarseness should seek medical evaluation to explore potential underlying causes, including parathyroid issues.

Difficulty Swallowing

Difficulty swallowing, or dysphagia, could also be one of the parathyroid tumor symptoms. Enlargement or invasion of surrounding structures by the tumor can impact the normal swallowing process. If difficulty swallowing persists, it is crucial to consult with healthcare professionals to determine the cause and appropriate course of action.

Causes of Parathyroid Cancer

Many often wonder, “What causes parathyroid cancer?” Reports suggest that certain genetic mutations can increase the risk of parathyroid cancer. The following are some of the possible causes of parathyroid tumors:

When to see an Oncologist?

Persistent fatigue, unexplained weight loss, or changes in voice and swallowing may indicate the presence of parathyroid cancer. Individuals with hereditary conditions identified as causes of parathyroid tumors, namely MEN1 or hyperparathyroidism-jaw tumor syndrome, and a history of radiation therapy should schedule regular check-ups with an oncologist.


Understanding parathyroid cancer is crucial for early detection and effective management. From recognizing symptoms to possible causes of parathyroid tumors, this knowledge empowers individuals to seek timely medical attention and adopt preventive measures.

Frequently Asked Questions

Survival rates for parathyroid cancer vary based on factors such as stage at diagnosis and treatment response. Advancements in medical care, early detection, and comprehensive treatment plans are significantly contributing to improved outcomes, potentially extending life expectancy.

High parathyroid levels, often associated with conditions like hyperparathyroidism, can manifest as symptoms such as fatigue, frequent urination, nausea, and muscle weakness. Identifying these symptoms prompts further evaluation to assess parathyroid function.

Parathyroid tumors are typically located behind the thyroid gland in the neck. While these small glands are challenging to feel, specialized imaging studies such as ultrasounds and scans help pinpoint their precise location for diagnostic purposes.

The parathyroid gland produces parathyroid hormone (PTH), a crucial regulator of calcium and phosphorus levels in the blood. PTH stimulates the release of calcium from bones and enhances calcium absorption in the intestines, maintaining overall calcium balance.

Parathyroid dysfunction, whether due to cancer or other conditions, can evoke various symptoms. Elevated PTH levels may cause fatigue, muscle weakness, and gastrointestinal issues. Prompt medical attention is essential to address these symptoms and determine the underlying cause for appropriate management.